Enhanced M-Folate 2,000 mcg

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Enhanced M-Folate 2K Supplement Facts.jpg
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Enhanced M-Folate 2,000 mcg

21.98

1,000 mcg vegetarian capsules

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  • Supports methylation and healthy serum folate levels
  • Supports nervous system health and normal cellular proliferation (red blood cells)
  • Supports a healthy pregnancy outcome

Enhanced M-Folate 2,000 provides 2,000 mcg of 5-MTHF (5-methyltetrahydrofolate) per serving. 5-MTHF is the most biologically active form of the water-soluble B vitamin, folate;  and it may be the preferred form for those with variations in digestion, absorption, or folate metabolism. Data suggest that in comparison to synthetic folic acid, 5-MTHF increases plasma folate more effectively. In this formula, 5-MTHF is provided as Quatrefolic®—the glucosamine salt of 5-MTHF. Quatrefolic has demonstrated greater stability, solubility, and bioavailability when compared to calcium salt forms of 5-MTHF.

5-MTHF is the most biologically active form of folate. It is the predominant type of folate present in food and the form into which the body must convert all other forms of folate. Along with vitamin B12, folate serves as a donor of methyl groups. The body utilizes methyl groups in many nervous system and metabolic processes, including the conversion of homocysteine to methionine, the synthesis of monoamine neurotransmitters, the production of melatonin, and the synthesis of DNA. In addition, sufficient folate is necessary for brain and nervous system functions and for a healthy pregnancy outcome.

In Prescription Lab's formulas, 5-MTHF is provided as Quatrefolic—the glucosamine salt of 5-MTHF. Quatrefolic is proven to have greater stability, solubility, and bioavailability over the commonly used calcium salt form of 5-MTHF. In a randomized crossover study, subjects received 400 mcg/d of Quatrefolic or 5-MTHF calcium salt. Titernormalized Cmax and AUC demonstrated a 10% higher bioavailability of Quatrefolic. Quatrefolic has several in vitro and in vivo preclinical and clinical studies to characterize and assure the safety profile of the product.


These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Read all product packaging for ingredients, suggested use, warnings, and other important information prior to use. The information contained on this web site is provided for informational purposes only and is not intended to substitute for the advice provided by your doctor or other health care professional.